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Medisearch Clinical Trials

1419 Village Drive

St. Joseph, Mo. 64506

Psoriasis Ages 18-75   
Clinical Trial: VY2024-03
Psoriasis clinical trial

Clinical Trial VY2024-03: Eligibility Criteria

We are conducting a clinical trial to evaluate a new treatment for moderate to severe plaque psoriasis. You may be eligible to participate if you meet the following criteria:​

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  • Age: 18 to 75 years old.

  • Diagnosis: Confirmed moderate to severe plaque psoriasis for at least 6 months.

  • Severity Measures:

    • Psoriasis Area and Severity Index (PASI) score ≥12.

    • Static Physician’s Global Assessment (sPGA) score ≥3.

    • Body Surface Area (BSA) involvement ≥10%.

  • Treatment History: Candidates for phototherapy or systemic therapy.

  • Body Weight and BMI: Total body weight ≥50 kg (110 lbs) and BMI between 18 and 35 kg/m².

If you are interested in participating or would like more information,just give us a call.

Understanding Psoriasis: Causes, Effects, and Emotional Impact

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What is Psoriasis?

Psoriasis is a chronic autoimmune skin condition characterized by the rapid buildup of skin cells, leading to scaling on the skin’s surface. This buildup causes inflammation and redness around the scales, commonly appearing on areas like elbows, knees, scalp, and lower back. The condition varies in severity and can range from small localized patches to complete body coverage. ​

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What Causes Psoriasis?

While the exact cause of psoriasis isn't fully understood, it's believed to be related to an immune system problem that causes skin cells to regenerate at faster-than-normal rates. Genetic factors and environmental triggers, such as infections, stress, and cold weather, can also play a role in the development and exacerbation of the condition.

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Physical Effects
  • Skin Lesions: Raised, red patches covered with silvery scales.

  • Itching and Burning: Affected areas can be itchy and may burn or sting.

  • Dry, Cracked Skin: Which may bleed.

  • Nail Changes: Thickened, pitted, or ridged nails.

  • Joint Pain: In some cases, psoriasis is associated with psoriatic arthritis, leading to swollen and painful joints.

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Emotional and Psychological Effects

Living with psoriasis can significantly impact mental health. Individuals may experience:​

  • Depression and Anxiety: Due to the chronic nature and visibility of the condition.

  • Social Isolation: Embarrassment or self-consciousness can lead to withdrawal from social activities.

  • Low Self-Esteem: Persistent skin issues can affect self-image and confidence

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Support and Treatment Options

While there's no cure for psoriasis, various treatments can help manage symptoms:​

  • Topical Treatments: Corticosteroids, vitamin D analogues, and moisturizers.

  • Phototherapy: Controlled exposure to ultraviolet light.

  • Systemic Medications: Oral or injected medications that affect the whole body.

  • Biologic Therapies: Target specific parts of the immune system.

  • Support Groups and Counseling: To address emotional and psychological challenges

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Medisearch Clinical Trials

1419 Village Drive

St. Joseph, Mo. 64506

Mon. - Thur.    8 am - 5 pm

Sat. - Sun.  Closed

816-364-1515

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Medisearch Clinical Trials

1427 Village Drive 

   Saint  Joseph. Mo 64506

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